I agree with iclund, Kawartha Lakes for numbers. We make the trip every September and usually get into numbers. Last year 8 guys, six days fished, 62 muskies landed....only 5 over 40'', largest at 45". My uncle has been making the trip for the past 20+ years, and that was by far the best year for numbers.
It's about an 8 hr drive from State College, not to bad.